DHC Pediatric Webinar - Respiratory Syncytial Virus (RSV): Infants, Asthma, and Prevention

Tuesday, September 10, 2024, 8:00 AM - Friday, September 10, 2027, 9:00 AM

AMA PRA Category 1 Credits™ (1.00 hours), ANCC Nursing Contact Hours (1.00 hours), CME-Designated Participation Credit (1.00 hours)

This Pediatric Lecture Series will discuss important pediatric topics that may lead to the improvement of child health from an individual, health care system and/or societal level.

Presenter

Brian O’Sullivan, MD, Section Chief, Pediatric Pulmonary, Dartmouth Hitchcock Medical Center

About our Presenter

Dr. O’Sullivan completed his undergraduate and medical school training at Dartmouth and moved on to Philadelphia for his residency, chief residency and fellowship at St Christopher’s. In addition to all of this training, he completed a master’s in Public Health in Medical Ethics at the Harvard School of Public Health. Dr. O’Sullivan has used this degree in his work and has an extensive CV of Publications as well. He is a Professor of Pediatrics at the Geisel School of Medicine as well as the Director of the NH Cystic Fibrosis Center.

1. Describe the impact of RSV on infants.
2. Explain the role of RSV infection on asthma.
3. Discuss prevention and treatment strategies for Respiratory Syncytial Virus (RSV).

In support of improving patient care, Dartmouth Health is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team. 

American Medical Association (AMA)
Dartmouth Health designates this Enduring Material for a maximum of 1.00 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

American Nurses Credentialing Center (ANCC)
Dartmouth Health designates this Enduring Material for a maximum of 1.00 ANCC contact hours.

All other learners may claim CME-designated participation credit. Consult your professional licensing board regarding the applicability and acceptance of CME-designated participation credit for programs certified for credit by organizations accredited by Joint Accreditation for Interprofessional Education.

Registration/Requirements for Successful Completion
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Bibliographic Material

• About RSV | RSV | CDC
  
  
• RSV and Underlying Conditions | RSV and Me
  
  
• Respiratory Syncytial Virus (RSV)- An Overview (microbenotes.com)
  
  
• RSV Seasonality by Year; MMWR Weekly April 7, 2023; 72(14):355–361
  
  
• Gatt D, Martin I, AlFouzan R, Moraes TJ. Prevention and Treatment Strategies for Respiratory Syncytial Virus (RSV). Pathogens. 2023 Jan 17;12(2):154. https://doi.org/10.3390/pathogens12020154. PMID: 36839426; PMCID: PMC9961958.
  
  
• Sam Ogozalek, Tampa Bay Times, July 31, 2024, Florida’s RSV Season Has Started, and It’s Coming Soon to the Rest of US. Here’s a Primer.
  
  
• *Am J Epidemiol 1969;89:422-34  §Curr Opin Virol 2013;3:332-42
  
  
• Hall CB, Douglas, RG, J Pediatr 1981;99:100-103
  
  
• Am J Dis Child  1987;141(6):695-97, How can we decrease the spread of RSV?
  
  
• MELODY Trial – complete data following COVID-19 Study of late pre-term and term infants (twice as many infants enrolled), N Engl J Med 388;16  April 20, 2023
  
  
• Bivalent prefusion F vaccine in pregnancy to prevent RSV illness in infants – NEJM 2023;388:1451-64 (Pfizer study)
  
  
• RSV prefusion F protein-based maternal vaccine – preterm birth and other outcomes – NEJM 2024;390:1009-21 (GSK study)
  
  
• NEJM 2023;388:1451-64; Pfizer vaccine in pregnant women
  
  
• Becker Y. Respiratory syncytial virus (RSV) evades the human adaptive immune system by skewing the Th1/Th2 cytokine balance toward increased levels of Th2 cytokines and IgE, markers of allergy--a review. Virus Genes. 2006 Oct;33(2):235-52. https://doi.org/10.1007/s11262-006-0064-x. PMID: 16972040.
  
  
• Viruses 2020, 12(5), 521; https://doi.org/10.3390/v12050521
  
  
• Respiratory syncytial virus infection during infancy and asthma during childhood in the USA (INSPIRE): a population-based, prospective birth cohort study Rosas-Salazar, Christian et al. The Lancet, Volume 401, Issue 10389, 1669 – 1680
  
  
• Guillermo Ezpeleta, Ana Navascués, Natividad Viguria, Mercedes Herranz-Aguirre, Sergio Enrique Juan Belloc, Juan Gimeno Ballester, Juan Carlos Muruzábal, Manuel García-Cenoz, Camino Trobajo-Sanmartín, Aitziber Echeverria, Iván Martínez-Baz, Noelia Vera-Punzano, Itziar Casado, Héctor López-Mendoza, Carmen Ezpeleta, Jesús Castilla,Effectiveness of Nirsevimab Immunoprophylaxis Administered at Birth to Prevent Infant Hospitalisation for Respiratory Syncytial Virus Infection: A Population-Based Cohort Study, Vaccines, 12, 4, (383), (2024). https://doi.org/10.3390/vaccines12040383
  
  
• Nirsevimab for Prevention of RSV in Healthy Late-Preterm and Term Infants Authors: Laura L. Hammitt, M.D., Ron Dagan, M.D. https://orcid.org/0000-0002-8888-1046, Yuan Yuan, Ph.D., Manuel Baca Cots, M.D., Miroslava Bosheva, M.D., Shabir A. Madhi, Ph.D. https://orcid.org/0000-0002-7629-0636, William J. Muller, Ph.D. https://orcid.org/0000-0001-7690-0695, +11, for the MELODY Study Group*Author Info & Affiliations Published March 2, 2022  N Engl J Med 2022;386:837-846 https://doi.org/10.1056/NEJMoa2110275 VOL. 386 NO. 9
  
  
• Single-Dose Nirsevimab for Prevention of RSV in Preterm Infants Authors: M. Pamela Griffin, M.D., Yuan Yuan, Ph.D., Therese Takas, B.S., Joseph B. Domachowske, M.D., Shabir A. Madhi, M.B., B.Ch., Ph.D., Paolo Manzoni, M.D., Ph.D., Eric A.F. Simões, M.D., +5, for the Nirsevimab Study Group*Author Info & Affiliations Published July 29, 2020 N Engl J Med 2020;383:415-425 https://doi.org/10.1056/NEJMoa1913556 VOL. 383 NO. 5
  
  

Provider Contact Information
Provider contact information for questions regarding accreditation of the activity:

Center for Learning and Professional Development
ACE Office
Dartmouth Health
[email protected]

Mitigation of Relevant Financial Relationships

Dartmouth Health adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education.  Any individuals in a position to control the content of a CE activity, including planners, faculty, authors, or others are required to disclose all financial relationships with ineligible companies^.  All relevant financial relationships have been mitigated prior to the commencement of the activity.

^Ineligible Company is any entity whose primary business purpose is producing, marketing, selling, re-selling or distributing healthcare products used by or on patients.